Top 5 Lidocaine Creams: Your Numbing Relief Guide

Ever wish you could just turn down the volume on discomfort? Imagine a little bit of magic cream that could help you feel less sting or soreness. That’s what many people hope for when they look into Lidocaine Cream.

But when you start looking, you might feel lost. So many brands, different strengths, and confusing labels! It’s tough to know which cream actually works best for your needs, whether it’s for a minor procedure, a tattoo session, or just everyday irritation. You want something effective but also safe.

This post cuts through the noise. We will break down what Lidocaine Cream really does, how to read those labels like a pro, and highlight the key things you need to check before you buy. By the end, you will feel confident choosing the right product.

Let’s dive in and uncover the secrets to finding your perfect topical numbing solution.

Top Lidocaine Cream Recommendations

No. 1
HealthWise Maximum OTC Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy | 2.7 Oz | Unscented Formula | Topical Anesthetic
  • MAXIMUM STRENGTH RELIEF — Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
  • FAST-ACTING LIDOCAINE — Containing 4% lidocaine, this cream works by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
  • NON-GREASY FORMULA — Non-greasy formula glides on smooth; safely apply every 6-8 hours, up to 3x daily
  • SUPPORT AND INSTRUCTION — Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
  • Compare to Aspercreme with Lidocaine active ingredients
No. 3
WELMATE 5% Lidocaine Cream for Hemorrhoids – Fast-Acting Lidocaine Numbing Cream & Topical Analgesic Cream for Anorectal Itch Relief, Unscented, Child Resistant Packaging 2 oz (60g)
  • Fast Acting Hemorrhoid Cream - Made with 5% Lidocaine, this topical anesthetic provides temporary relief from discomfort, itching, and burning associated with hemorrhoids and other anorectal irritation.
  • Maximum Strength Lidocaine Cream - Delivers doctor-recommended strength with the highest percentage of Lidocaine available over the counter to help soothe targeted external discomfort fast.
  • External Use Only, Made for Sensitive Skin - Formulated for delicate areas, this cream is designed for external, anorectal use and is gentle on all skin types. Packaging is child-resistant for added peace of mind.
  • How to Use - Clean the area with soap and water, rinse thoroughly, and pat dry. Apply external pain relief cream up to 6 times per day. Our cream is cruelty-free, non-greasy, odorless, and free from harsh chemicals.
  • Why WELMATE? - Founded in 2020 by former pharmacy employees who were fed up with the pricing of over-the-counter medication. Today, we continue to bring affordable health and wellness products to your doorstep as America's trusted OTC store.
No. 4
Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical Anesthetic with Allantoin, Vitamin E for Local and Anorectal Uses, Hemorrhoid Treatment, 1.35 Oz
  • FSA HSA Eligible OTC Medications & Treatments - This topical lidocaine numb cream with Allantoin, clinically proven to temporarily relieve pain, burning, itching, and discomfort, reduces inflammation and soreness in local and anorectal areas
  • 5% Lidocaine Cream Maximum Strength - This pain relief anti itch cream provides immediate relief for minor aches, minor burns, and minor skin irritations. It also works for postpartum relief, hemorrhoid shrinking treatment, and anorectal disorders
  • Enhanced Liposomal Deep Penetrating Skin Numbing Cream - Best efficacy, fast-acting & long-lasting. It begins numbing in 3-5 minutes, peaks after 20-25 minutes, and lasts 1 hour from its peak. Numbing performance may vary depending on the thickness of the skin area and individual metabolism
  • Oil-Free, Odor-Free & Non-Greasy - Hypoallergenic, no harsh chemicals, non-addictive. Apply before, during, and after treatment, may reapply halfway for enhanced effect. Water-based formula for easy application and no-mess removal
  • Made in USA in an FDA Registered Facility - Cruelty-Free, cGMP Certified, secured with a child-resistant cap. A performance test before treatment is highly recommended to assess your best performance timing
No. 5
Neosporin + Lidocaine First Aid Triple Antibiotic Ointment, Fast-Acting, Maximum Strength Topical Pain Relief, 24-Hour Infection Protection That Numbs Away The Pain for Minor Wound Care, 0.5 oz
  • .5-ounce tube of Neosporin + Lidocaine First Aid Triple Antibiotic Ointment, by the #1 doctor-recommended brand, has an effective germ-killing formula for 24-hour long-lasting infection protection and fast-acting numbing pain relief for minor wounds
  • Pain relief ointment formulated with triple antibiotic combination of infection-protection ingredients bacitracin zinc, neomycin sulfate and polymyxin B sulfate to help prevent infections in minor cuts, scrapes, and wounds for minor wound care treatment
  • Triple antibiotic ointment also contains fast-acting lidocaine, a topical analgesic that numbs away the pain, for maximum-strength burn pain relief and long-lasting infection protection from painful minor cuts, scrapes, burns, and wounds
  • First aid essential in a compact and portable 0.5-ounce tube, suitable in wound care supplies and first aid kits for home, on-the-go, cars, dorms, travel, camping, and outdoors, provides effective triple antibiotic protection for treatment of minor wounds
  • To use, clean affected area with a BAND-AID Brand Antiseptic Spray and treat with a small amount of first aid topical antibiotic ointment one to three times daily. Cover the minor wound with a BAND-AID Brand Adhesive Bandage for extra protection
No. 6
HealthWise Lidocaine Plus+ Cream | Numbs Away Pain | | Non-Greasy | 3.0 Oz | 4% OTC Lidocaine + 10% Benzyl Alcohol | Topical Anesthetic
  • MAXIMUM STRENGTH RELIEF — Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
  • PAIN RELIEVING LIDOCAINE + BENZYL ALCOHOL — Powerful pain relief ingredients: 4% lidocaine plus 10% benzyl alcohol work together by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
  • NON-GREASY FORMULA — Non-greasy formula goes on smooth; safely apply 3-4 times daily
  • 30-APPLICATIONS PER TUBE — Only a dime size of cream is needed per application to targeted areas for up to 30 applications in each tube
  • SUPPORT AND INSTRUCTION — Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
No. 7
WELMATE 5% Lidocaine Cream for Hemorrhoids, 6 oz Jar – Fast-Acting Lidocaine Numbing Cream & Topical Analgesic Cream for Anorectal Itch Relief
  • Fast Acting Hemorrhoid Cream - Made with 5% Lidocaine, this topical anesthetic provides temporary relief from discomfort, itching, and burning associated with hemorrhoids and other anorectal irritation.
  • Maximum Strength Lidocaine Cream - Delivers doctor-recommended strength with the highest percentage of Lidocaine available over the counter to help soothe targeted external discomfort fast.
  • External Use Only, Made for Sensitive Skin - Formulated for delicate areas, this cream is designed for external, anorectal use and is gentle on all skin types. Packaging is child-resistant for added peace of mind.
  • How to Use - Clean the area with soap and water, rinse thoroughly, and pat dry. Apply external pain relief cream up to 6 times per day. Our cream is cruelty-free, non-greasy, odorless, and free from harsh chemicals.
  • Why WELMATE? - Founded in 2020 by former pharmacy employees who were fed up with the pricing of over-the-counter medication. Today, we continue to bring affordable health and wellness products to your doorstep as America's trusted OTC store.
No. 8
Aspercreme Essential Oils Lidocaine Pain Relief with No-Mess Roll-On Applicator, Max-Strength Lidocaine Numbs Away Nerve Pain, Moisturizing Aloe Hydrates Skin, Lavender, 2.5 Oz.
  • Contains one (1) 2.5-oz. roll-on bottle of Aspercreme Essential Oils Lidocaine Pain Relief Liquid With No-mess Applicator, Lavender
  • Fast-Acting Relief: Max-strength 4% lidocaine topical numbing liquid targets nerves and numbs away pain
  • No-Mess Application: Convenient roll-on applicator offers targeted relief and keeps hands clean
  • Non-greasy Formula: Aspercreme doesn't leave behind greasy residue or strong odor
  • Maximum-Strength Lidocaine: OTC Aspercreme offers the maximum-strength lidocaine pain relief available without a prescription and is FSA/HSA eligible

The Ultimate Buying Guide for Numbing Relief: Choosing the Right Lidocaine Cream

Lidocaine cream is a topical anesthetic. It helps block the feeling of pain in a small area. People use it for minor skin procedures, sunburn, or discomfort. Finding the best cream matters for safe and effective relief. This guide helps you select the perfect product.

Key Features to Look For in Lidocaine Cream

When shopping for lidocaine cream, certain features make a product better. You need to check the active ingredient strength and how fast it works.

1. Lidocaine Concentration

This is the most important feature. Most over-the-counter (OTC) creams contain 2.5% to 5% lidocaine. Higher percentages usually offer stronger numbing but may require a doctor’s prescription. For minor needs, 4% or 5% is often enough. Always follow the package directions based on the concentration.

2. Speed of Action

How quickly does the cream start working? Some creams begin numbing within 15 to 30 minutes. Others might take up to an hour. If you need fast relief, look for formulas advertised as “fast-acting.”

3. Size and Packaging

Consider how often you will use it. Creams come in tubes or pump bottles. Pump bottles often dispense a more controlled amount, which reduces waste.

Important Materials and Ingredients

Lidocaine is the main active material. However, other ingredients affect the cream’s quality and how it feels on your skin.

  • Active Ingredient: Pure Lidocaine Hydrochloride. Ensure the label clearly lists this.
  • Inactive Ingredients (Base): Look at the base ingredients. Water-based gels absorb faster. Oil-based creams might last longer on the skin but can feel greasy.
  • Soothing Additives: Many quality creams include aloe vera, Vitamin E, or chamomile. These ingredients help calm the skin while the lidocaine works.

Factors That Improve or Reduce Quality

The quality of a lidocaine cream is not just about the lidocaine percentage. How the product is made matters greatly.

Factors That Improve Quality:

  • Penetration Enhancers: Some formulas include ingredients that help the lidocaine travel deeper into the skin layers. This leads to better, longer-lasting numbness.
  • pH Balance: A balanced pH helps the cream absorb smoothly without causing immediate stinging upon application.
  • Non-Comedogenic Formulas: If you have sensitive or acne-prone skin, choose a formula that will not clog pores.

Factors That Reduce Quality:

  • High Alcohol Content: Too much alcohol in the formula can dry out the skin severely, causing irritation rather than relief.
  • Strong Perfumes or Dyes: These additives increase the risk of allergic reactions or skin sensitivity, especially when the skin is already irritated.

User Experience and Common Use Cases

How you plan to use the cream heavily influences your best choice.

Common Use Cases:

  • Tattooing/Piercing: Users need maximum numbing time (often 45-60 minutes) before the procedure starts. Stronger, thicker creams work best here.
  • Minor Cuts or Bug Bites: Quick, targeted relief is necessary. A thinner, fast-absorbing gel is ideal for small spots.
  • Sunburn Relief: If the skin is already damaged, a cream with added cooling agents (like menthol, used sparingly) improves the overall soothing effect.

Application Tip: Always test a small patch of skin first. Wait 24 hours. If you see redness or itching, do not use the product widely.


10 Frequently Asked Questions (FAQ) About Lidocaine Cream

Q: Is lidocaine cream the same as numbing cream?

A: Yes, usually. Lidocaine is the most common active ingredient found in over-the-counter numbing creams.

Q: Can I buy lidocaine cream without a prescription?

A: Yes, many concentrations (usually up to 4% or 5%) are sold over-the-counter (OTC) in pharmacies.

Q: How long does the numbing effect usually last?

A: The numbing effect generally lasts between one to three hours after application, depending on the concentration and how deeply it absorbed.

Q: What is the safest lidocaine concentration to start with?

A: Most people start with a 4% or 5% OTC cream. Higher concentrations require a doctor’s approval.

Q: Can I use lidocaine cream on broken skin?

A: No. You should never apply lidocaine cream to cuts, scrapes, or any broken skin unless specifically directed by a doctor.

Q: Are there side effects associated with lidocaine cream?

A: Common side effects include temporary redness, mild swelling, or a slight burning sensation upon initial application.

Q: How should I store my lidocaine cream?

A: Store the cream in a cool, dry place, away from direct sunlight. Keep it out of reach of children.

Q: Does the cream leave a greasy residue?

A: Water-based gels tend to absorb cleaner. Oil-based formulas may leave a slightly heavier residue on the skin.

Q: Will the cream stain my clothes?

A: Most modern formulas are designed not to stain, but it is best to wait until the cream is fully absorbed before dressing.

Q: When should I stop using the cream and call a doctor?

A: Stop use immediately if you experience difficulty breathing, severe rash, dizziness, or unusual heart rhythms. These are signs of a serious reaction.